Products made using hemp-derived cannabidiol (CBD) like oils, edibles, and creams are extremely popular among users. This is mainly because of their anti-inflammatory and analgesic effects along with other therapeutic effects. Cannabidiol health and wellness products are especially useful for treating the symptoms of arthritis, like inflammation and pain. They are a better option than pharmaceutical drugs like steroids or corticosteroids and painkillers, because of CBD’s lack of side effects. Also, it does not pose the risk of addiction. Read on to know more about using CBD for inflammation, arthritis, and other health issues.
Overview About Inflammation
Inflammation is a normal physiological response to diseases or injuries. But when this becomes chronic, it is a cause of concern as it leads to the development of other diseases. Arthritis is an autoimmune disease that is characterized by the inflammation of the synovium, the soft tissue that lines the joints. Apart from this, chronic stress, pollution, and other environmental factors also trigger the inflammatory response of the body. Also, keep in mind that it is not always easy to detect or diagnose chronic inflammation, and this makes the condition more dangerous. Furthermore, cardiovascular inflammation is one of the major reasons for many cardiac health issues.
Scientific surveys conducted in the last few decades have linked chronic inflammation to numerous health conditions. For example, it is one of the causes of cancer, Alzheimer’s disease, and cardiovascular issues. Also, studies on Alzheimer’s disease have shown that this neurodegenerative condition is characterized by elevated levels of inflammatory markers. As the inflammation increases, cognitive deterioration speeds up, increasing the severity of other symptoms of this disease.
Listed below are health issues and diseases linked to inflammation:
- Heart disease
- Alzheimer’s disease
- Rheumatoid arthritis
The Inflammatory Response
Inflammation is a natural response of the body to protect it from injures, infection, and illness. It is mainly mediated by the immune system that has receptors spread throughout the body; its purpose is to protect the body from foreign substances. Sometimes, in this process, it destroys healthy cells and tissues to prevent the threat from spreading and ensure long-term overall protection of the body.
When a body part is injured, you experience swelling, pain, redness, heat, and often impaired function. This whole gamut of symptoms is inflammation, and it happens due to increased blood flow to the injured area to bring more immune cells. Moreover, the inflammatory response is also triggered by inflammatory molecules.
A normally functioning immune system can identify dangers and produce an inflammatory response when necessary to protect the body from further damage or danger. Once the danger is over, the inflammatory response is stopped so the body can recover by healing the damage or injury. This is done by the release of anti-inflammatory compounds that are carried by the bloodstream.
However, nowadays, our body receives many of these inflammatory triggers through food, pollutants in the air, the water we use, and so on. This keeps the immune system under constant fight and leads to chronic inflammation. Often these inflammatory triggers originate from the digestive tract. In addition, fat cells produce low levels of systemic inflammation in obese individuals.
Cannabidiol (CBD) To Fight Inflammation
Conventional treatments use steroids or corticosteroids to treat inflammation, and they are bad for health when used long-term. One of the safer alternate options is cannabidiol derived from the hemp plant. One of the major CBD uses is that it is effective for reducing inflammation because of its positive effect on the endocannabinoid system (ECS).
There are multiple molecular pathways by which cannabidiol produces its anti-inflammatory effect, and they are explained in detail below:
- Prostaglandins: One of the main reasons for CBD’s anti-inflammatory effect is that it inhibits the enzyme COX-2 that produces inflammatory prostaglandins.
- PAARγ: CBD stimulates the PAARγ receptor that is found on the nucleus of cells, and this affects the expression of its genes. This results in increased production of antioxidants and a reduction in the production of inflammatory molecules. Due to this, cannabidiol (CBD) has therapeutic uses in treating multiple sclerosis, Alzheimer’s disease, ulcerative colitis.
- Tumor Necrosis Factor (TNFα): Studies have shown that CBD is effective in protecting joints from inflammatory arthritis damage because it reduces the production of tumor necrosis factor (TNFα).
CBD Uses For Arthritis
Cannabidiol products like oils and topicals are useful for treating the symptoms of rheumatoid arthritis, especially inflammation. Ingesting CBD oil gives systemic relief from the inflammation and applying topical CBD on the inflamed joint gives quick localized relief by reducing the inflammation. When these two methods are combined, it slows down the progress of the disease, reduces the damage to joints, and improves the mobility of patients suffering from this condition. Having said that, there is the risk of CBD interacting with certain medications, particularly those with grapefruit warning. So, you must consult with the physician before using cannabidiol (CBD) for treating the symptoms of rheumatoid arthritis.
We hope that the details shared above clarified your doubt about CBD uses for treating inflammation, arthritis, and other health issues.